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pentobarbital will lower the extent or outcome of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Coadministration of CYP3A4 inducers may well minimize sufentanil